Use of Thiopurine Drugs

uses-of-thiopurines-mainThe class of drugs known as thiopurines includes multiple drugs, such as azathioprine (Imuran®), mercaptopurine (Purinethol®), and thioguanine (6-TG, Tabloid® or Lanvis®). These medications are used for the following reasons:

Azathioprine (Imuran®)

  • To prevent rejection after a kidney transplant
  • To reduce signs and symptoms of rheumatoid arthritis

Mercaptopurine (Purinethol®)

  • As maintenance therapy for acute lymphocytic leukemia

Thioguanine (6-TG, Tabloid® or Lanvis®)

  • To induce remission in patients with acute nonlymphocytic leukemia

Thiopurine drugs may also be used to treat other autoimmune disorders including Crohn's disease, ulcerative colitis, and lupus.

Where Can I Get More Information?
The Coriell Personalized Medicine Collaborative research study has a board-certified genetic counselor that is available to talk with you about the information you may learn as a result of being in the study. Click here for more information. If you would like to talk with a CPMC genetic counselor, email us at This email address is being protected from spambots. You need JavaScript enabled to view it. . For more information about thiopurines:

Medline Plus Summary Summary

Medline Plus Summary Summary

Medline Plus Summary Summary

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