Use of Thiopurine Drugs

uses-of-thiopurines-mainThe class of drugs known as thiopurines includes multiple drugs, such as azathioprine (Imuran®), mercaptopurine (Purinethol®), and thioguanine (6-TG, Tabloid® or Lanvis®). These medications are used for the following reasons:


Azathioprine (Imuran®)

  • To prevent rejection after a kidney transplant
  • To reduce signs and symptoms of rheumatoid arthritis

Mercaptopurine (Purinethol®)

  • As maintenance therapy for acute lymphocytic leukemia

Thioguanine (6-TG, Tabloid® or Lanvis®)

  • To induce remission in patients with acute nonlymphocytic leukemia

Thiopurine drugs may also be used to treat other autoimmune disorders including Crohn's disease, ulcerative colitis, and lupus.

Where Can I Get More Information?
The Coriell Personalized Medicine Collaborative research study has a board-certified genetic counselor that is available to talk with you about the information you may learn as a result of being in the study. Click here for more information. If you would like to talk with a CPMC genetic counselor, email us at This email address is being protected from spambots. You need JavaScript enabled to view it. . For more information about thiopurines:

Thioguanine
Medline Plus Summary
Drugs.com Summary

Azathioprine
Medline Plus Summary
Drugs.com Summary

Mercaptopurine
Medline Plus Summary
Drugs.com Summary

To search for specific drugs by brand name or generic name at drugs@FDA, click here.

To report an adverse reaction to a medication to the FDA, click here.