The CPMC Study and Simvastatin (Zocor®)

What Does the CPMC Test For?

The CPMC evaluates 4 variants in the SLCO1B1 gene associated with liver uptake activity and altered simvastatin (Zocor®) drug response. Your personal result will be displayed in the form of a table on the YOUR GENETIC RESULT tab within your personal report. Your result interpretation can be found on a separate YOUR RESULT INTERPRETATION tab.

Sample Report
simvastatin-cpmc-graph-1 

In addition to the YOUR GENETIC RESULTS tab, which will show your personal result for each variant tested, you will be provided with an interpretation (found on the YOUR RESULT INTERPRETATION tab). The interpretation will give you information about how your personal genetic results will impact your predicted response to simvastatin (Zocor®). In some cases this information will not be known.

Sample Report
simvastatin-cpmc-graph-2 

CPMC Test and Report Limitations

It is important to note that CPMC testing alone cannot fully predict your response to simvastatin (Zocor®) or any other drug or class of drugs. Other factors like body weight, other health conditions, and other medications may also influence the way a person will respond to simvastatin (Zocor®) and other drugs. It is possible that you may have other genetic variants that occur in the SLCO1B1 gene that are not tested by the CPMC. Also, it is possible that you may have variants in other genes that influence your response to simvastatin (Zocor®).