Proton Pump Inhibitors

By: CPMC Genetic Counseling Staff
Reviewed by: Laura Hodges, PhD and Neda Gharani, PhD, Coriell Institute for Medical Research

Proton pump inhibitors (PPIs) are a class of drugs that reduce the amount of acid made by the stomach. Examples of proton pump inhobitor drugs include omeprazole (Prilosec®, Zegerid®), lansoprazole (Prevacid®), pantoprazole (Protonix®), rabeprazole (Aciphex®), esomeprazole (Nexium®), and dexlansoprazole (Kapidex®/Dexilant®).

How Often Are Proton Pump Inhibitors Prescribed?
In 2009, 119.4 million prescriptions were written for proton pump inhibitors, making them the sixth most commonly prescribed type of drug sold in the United States1.


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Learn more about proton pump inhibitor drugs and understand your likely response to these drugs through the links below.

Page References

Use of Proton Pump Inhibitors

Learn more about Proton Pump Inhibitors [ Learn More › ]

Risk Factors

Both genetic and non-genetic factors affect how your body processes Proton Pump Inhibitors [ Learn More › ]

Reduce Your Risk

Reduce your risk for an undesired response to Proton Pump Inhibitors [ Learn More › ]

The CPMC Study

Learn how the CPMC Study identifies your response to Proton Pump Inhibitors [ Learn More › ]