Paroxetine (Paxil®)

By: Neda Gharani, PhD, and Andrew Brangan, CPMC Research Analyst
Reviewed by: Wendy Roberts, PhD, Coriell Institute for Medical Research

Paroxetine (Paxil®) is a type of antidepressant drug known as a selective serotonin reuptake inhibitor (SSRI) and is primarily used to treat people with psychiatric disabilities, such as depression. In these disorders, natural chemicals in the brain, like serotonin, may be unbalanced. Paroxetine (Paxil®) works by blocking the reabsorption, or reuptake, of serotonin, thereby increasing the amount of serotonin in the brain.

How Often is Paroxetine Prescribed?
With over 15 million prescriptions made in the U.S. in 2014, paroxetine was ranked 57th among the top 200 of total prescriptions (

Learn more about paroxetine (Paxil®) and understand your likely response to this drug through the links below.

Uses of Paroxetine (Paxil®)

Learn more about paroxetine (Paxil®)
Learn More› ]

Risk Factors

Both genetic and non-genetic factors affect how your body processes paroxetine (Paxil®
Learn More› ]

Reduce Your Risk

Reduce your risk for an undesired response to paroxetine (Paxil®)
Learn More› ]

The CPMC Study

Learn how the CPMC Study identifies your response to paroxetine (Paxil®)
Learn More› ]